COL25A1 Polyclonal Antibody


COL25A1 Polyclonal Antibody

Cat No.:HR1AP8873
Product available

  Product info

Alternative Name: COL25A1; Collagen alpha-1(XXV) chain; Alzheimer disease amyloid-associated protein; AMY; CLAC-P

Antibodies Type: polyclonal



Product Details

Product Name COL25A1 Polyclonal Antibody
Cat NumberHR1AP8873
SourceRabbit
ApplicationsWB,IHC-p,IF,ELISA
Species Reactivity Human,Mouse
Storage -20°C/1 year
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration 1 mg/ml
Observed Band 64
Gene ID COL25A1
Alternative Name COL25A1; Collagen alpha-1(XXV) chain; Alzheimer disease amyloid-associated protein; AMY; CLAC-P
Background collagen type XXV alpha 1 chain(COL25A1) Homo sapiens This gene encodes a brain-specific membrane associated collagen. A product of proteolytic processing of the encoded protein, CLAC (collagenous Alzheimer amyloid plaque component), binds to amyloid beta-peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410). A study of over-expression of this collagen in mice, however, found changes in pathology and behavior suggesting that the encoded protein may promote amyloid plaque formation (PMID: 19548013). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011],
Type polyclonal

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