Product Name | Cadherin-20 Polyclonal Antibody |
Cat Number | HR1AP6689 |
Source | Rabbit |
Applications | IHC-p,IF,ELISA |
Species Reactivity | Human,Mouse,Rat |
Storage | -20°C/1 year |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration | 1 mg/ml |
Gene ID | CDH20 |
Alternative Name | CDH20; CDH7L3; Cadherin-20 |
Background | cadherin 20(CDH20) Homo sapiens This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes. [provided by RefSeq, Jul 2008], |
Type | polyclonal |