Product Name | OB-cadherin Polyclonal Antibody |
Cat Number | HR1AP5533 |
Source | Rabbit |
Applications | WB,ELISA |
Species Reactivity | Human,Mouse |
Storage | -20°C/1 year |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration | 1 mg/ml |
Observed Band | 85 |
Gene ID | CDH11 |
Alternative Name | CDH11; Cadherin-11; OSF-4; Osteoblast cadherin; OB-cadherin |
Background | cadherin 11(CDH11) Homo sapiens This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008], |
Type | polyclonal |