Product Name | CD50 (phospho Ser518) Polyclonal Antibody |
Cat Number | HR1AP6921 |
Source | Rabbit |
Applications | WB,ELISA |
Species Reactivity | Human |
Storage | -20°C/1 year |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration | 1 mg/ml |
Observed Band | 42-60 |
Gene ID | ICAM3 |
Alternative Name | ICAM3; Intercellular adhesion molecule 3; ICAM-3; CDw50; ICAM-R; CD antigen CD50 |
Background | intercellular adhesion molecule 3(ICAM3) Homo sapiens The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016], |
Type | polyclonal |