Caspase-1 Polyclonal Antibody


Caspase-1 Polyclonal Antibody

Cat No.:HR1AP9572
Product available

  Product info

Alternative Name: caspase-1,caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase),CASP1,CASP-1

Antibodies Type: polyclonal



Product Details

Product Name Caspase-1 Polyclonal Antibody
Cat NumberHR1AP9572
SourceRabbit
ApplicationsIF,WB,IHC-p,ELISA
Species Reactivity Human,Rat
Storage -20°C/1 year
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration 1 mg/ml
Observed Band 35
Gene ID CASP1 IL1BC IL1BCE
Alternative Name caspase-1,caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase),CASP1,CASP-1
Background caspase 1(CASP1) Homo sapiens This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012],
Type polyclonal

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