| Product Name | CRSP150 Polyclonal Antibody |
| Cat Number | HR1AP9120 |
| Source | Rabbit |
| Applications | IHC-p,IF,ELISA |
| Species Reactivity | Human,Mouse |
| Storage | -20°C/1 year |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Gene ID | MED14 |
| Alternative Name | MED14; ARC150; CRSP2; CXorf4; DRIP150; EXLM1; RGR1; TRAP170; Mediator of RNA polymerase II transcription subunit 14; Activator-recruited cofactor 150 kDa component; ARC150; Cofactor required for Sp1 t |
| Background | mediator complex subunit 14(MED14) Homo sapiens The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation. [provided by RefSeq, Jul 2008], |
| Type | polyclonal |