Kininogen 1 Rabbit pAb


Kininogen 1 Rabbit pAb

Cat No.:HR1APEA367
Product available

  Product info

Alternative Name: BDK, Fitzgerald factor, HMWK, Ile Ser Bradykinin Bradykinin, Kallidin I Lysyl bradykinin, kininogen 1, KNG, KNG1

Antibodies Type: polyclonal



Product Details

Product Name Kininogen 1 Rabbit pAb
Cat NumberHR1APEA367
SourceRabbit
ApplicationsWB, IHC
Species Reactivity Human,Mouse,Rat
Recommended Dilutions WB 1:1500-1,000  IHC 1:100-200
Specificity Human
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality Polyclonal
Isotope IgG
Concentration 1mg/ml
Observed Band 45-120kDa
Gene ID 3827
Alternative Name BDK, Fitzgerald factor, HMWK, Ile Ser Bradykinin Bradykinin, Kallidin I Lysyl bradykinin, kininogen 1, KNG, KNG1
Background  Kininogens are inhibitors of thiol proteases;  HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes;  the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects. LMW-kininogen inhibits the aggregation of thrombocytes;  LMW-kininogen is in contrast to HMW-kininogen not involved in blood clottingUCHL1, UCHL3, UCHL5/UCH37, and BRCA-1-associated protein-1 (BAP1) belong to the UCH family of DUBs, which all posses a conserved catalytic domain (UCH domain) of about 230 amino acids.  UCHL1 is abundantly expressed in neuronal tissues and testes. 
Type polyclonal

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