Acetyl NF kB P65?K314/K315) (5G11) Mouse mAb


Acetyl NF kB P65?K314/K315) (5G11) Mouse mAb

Cat No.:HR1AM2488
Product available

  Product info

Alternative Name: NF kappa B p65, NFKB3, p65, p65 NF kB, RELA, TF65, Transcription Factor p65

Antibodies Type: monoclonal



Product Details

Product Name Acetyl NF kB P65?K314/K315) (5G11) Mouse mAb
Cat NumberHR1AM2488
SourceMouse
ApplicationsIHC
Species Reactivity Human,Mouse,Rat
Recommended Dilutions IHC 1:100-200
Specificity Human
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality Monoclonal
Isotope IgG1
Concentration 1mg/ml
Observed Band 65kDa
Gene ID 5970
Alternative Name NF kappa B p65, NFKB3, p65, p65 NF kB, RELA, TF65, Transcription Factor p65
Background NFkB p65 is ubiquitinated leading to its proteosomal degradation, which is required for termination of the NFkB response. Phosphorylation of NFkB p65 on S536 stimulates acetylation of K310 by CBP, enhancing transcriptional activity. NFkB p65 is also acetylated at K122, enhancing DNA binding and impairing the interaction with NFKBIA. The protein is deacetylated by HDAC3. Invasion of a host by a pathogen is frequently associated with the activation of NF-kB, which coordinates various aspects of immune function required for resistance to infection.
Type monoclonal

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