| Product Name | IDE/Insulin Degrading Enzyme Mouse mAb |
| Cat Number | HR1AM2194 |
| Source | Mouse |
| Applications | WB, IHC |
| Species Reactivity | Human |
| Recommended Dilutions | WB 1:1,000 IHC 1:200 |
| Specificity | Human |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Monoclonal |
| Isotope | IgG1 |
| Concentration | 1mg/ml |
| Observed Band | 118kDa |
| Gene ID | 3416 |
| Alternative Name | Abeta degrading protease, insulin degrading enzyme, Insulin protease, Insulinase, INSULYSIN |
| Background | Insulin Degrading Enzyme (IDE) is a large zinc-binding protease of the M16A metalloprotease subfamily known to cleave multiple short polypeptides that vary considerably in sequence. IDE was first identified by its ability to degrade the B chain of the hormone insulin. This activity was observed over fifty years ago, though the enzyme specifically responsible for B chain cleavage was identified more recently. |
| Type | monoclonal |