| Product Name | ATG5 (3C7) Mouse mAb |
| Cat Number | HR1AM2485 |
| Source | Mouse |
| Applications | WB, IHC |
| Species Reactivity | Human,Mouse,Rat |
| Recommended Dilutions | WB 1:5,000-10,000 IHC 1:100-200 |
| Specificity | Human |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Monoclonal |
| Isotope | IgG1 |
| Concentration | 1mg/ml |
| Observed Band | 55kDa |
| Gene ID | 9494 |
| Alternative Name | APG5, APG5L, ASP, Autophagy protein 5 antibody |
| Background | Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with a number of physiological processes including development, differentiation, neurodegeneration, infection, and cancer. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10. |
| Type | monoclonal |