| Product Name | ErbB-2/HER-2 Mouse mAb |
| Cat Number | HR1AM2190 |
| Source | Mouse |
| Applications | WB, IHC |
| Species Reactivity | Human |
| Recommended Dilutions | WB 1:1,000 IHC 1:200-500 |
| Specificity | Human |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Monoclonal |
| Isotope | IgG1 |
| Concentration | 1mg/ml |
| Observed Band | 138kDa |
| Gene ID | 2064 |
| Alternative Name | CD340, HER 2/neu, HER2, MLN 19, MLN19, NEU, NGL, p185, p185erbB2, Proto oncogene c ErbB 2, Proto oncogene Neu, TKR1 |
| Background | ErbB 2 is a receptor tyrosine kinase of the ErbB 2 family. It is closely related instructure to the epidermal growth factor receptor. ErbB 2 oncoprotein is detectable in a proportion of breast and other adenocarconomas, as well as transitional cell carcinomas. In the case of breast cancer, expression determined by immunohistochemistry has been shown to be associated with poor prognosis. |
| Type | monoclonal |