| Product Name | CD5 Mouse mAb |
| Cat Number | HR1AM2182 |
| Source | Mouse |
| Applications | IHC |
| Species Reactivity | Human,Rat,Mouse |
| Recommended Dilutions | IHC 1:100-200 |
| Specificity | Human |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Monoclonal |
| Isotope | IgG1 |
| Concentration | 1mg/ml |
| Observed Band | N/A |
| Gene ID | 921 |
| Alternative Name | CD5 molecule, LEU1, Lymphocyte antigen T1/Leu 1, T1 |
| Background | CD5 is a cluster of differentiation found on a subset of IgM-secreting B cells called B-1 cells, and also on T cells. B-1 cells have limited diversity of their B-cell receptor due to their lack of the enzyme terminal deoxynucleotidyl transferase (TdT) and are potentially self-reactive. CD5 serves to mitigate activating signals from the BCR so that the B-1 cells can only be activated by very strong stimuli (such as bacterial proteins) and not by normal tissue proteins. |
| Type | monoclonal |