Product Name | NBR1 (7C3) Mouse mAb |
Cat Number | HR1AM2484 |
Source | Mouse |
Applications | IHC |
Species Reactivity | Human,Mouse,Rat |
Recommended Dilutions | IHC 1:100-200 |
Specificity | Human |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
Clonality | Monoclonal |
Isotope | IgG1 |
Concentration | 1mg/ml |
Observed Band | 120kDa |
Gene ID | 4077 |
Alternative Name | 1A13B, MIG19, Nbr1 |
Background | NBR1 protein is known for its encoding gene proximity to the BRCA1 tumor suppressor gene. N-terminal Phox and Bem1p (PB1) domains of NBR1 mediate its interaction with muscle specific titin kinase and scaffolding protein p62. NBR1 plays a role in autophagy by facilitating the autophagosomal degradation of ubiquitinated proteins independently and also in concert with p62. |
Type | monoclonal |