Product Name | CD23 Mouse mAb |
Cat Number | HR1AM2160 |
Source | Mouse |
Applications | IHC |
Species Reactivity | Human,Rat,Mouse |
Recommended Dilutions | IHC 1:200 |
Specificity | Human |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
Clonality | Monoclonal |
Isotope | IgG1 |
Concentration | 1mg/ml |
Observed Band | 28,38,49kDa |
Gene ID | 2208 |
Alternative Name | BLAST 2, CD23A, CLEC4J, Fc epsilon RII, FCE2, FCER2, IGEBF, Lymphocyte IgE receptor |
Background | The CD23 antigen is the low affinity IgE Fc receptor, which is a 49 kDa protein with 38 and 28 kDa fragments. It is expressed on most mature, conventional B cells and can also be found on the surface of T cells, macrophages, platelets and EBV transformed B lymphoblasts. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic Lymphocytic leukemia. CD23 is expressed by B cells in the follicular mantle but not by proliferating germinal centre cells. CD23 is also expressed by eosinophils. |
Type | monoclonal |