Product Name | AMACR/P504S Mouse mAb |
Cat Number | HR1AM2158 |
Source | Mouse |
Applications | WB, IHC |
Species Reactivity | Human,Rat,Mouse |
Recommended Dilutions | WB 1:1,000 IHC 1:200 |
Specificity | Human |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
Clonality | Monoclonal |
Isotope | IgG1 |
Concentration | 1mg/ml |
Observed Band | 42kDa |
Gene ID | 23600 |
Alternative Name | Alpha-Methylacyl Coenzyme A Racemase ;RACE; 2-methylacyl-CoA racemase |
Background | AMACR has been recently described as prostate cancer-specific gene that encodes a protein involved in the beta-oxidation of branched chain fatty acids. Expression of AMACR protein is found in prostatic adenocarcinoma but not in benign prostatic tissue. It stains premalignant lesions of prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia. |
Type | monoclonal |