Product Name | Myosin IXb Polyclonal Antibody |
Cat Number | HR1AP7431 |
Source | Rabbit |
Applications | WB,ELISA |
Species Reactivity | Human,Mouse,Rat |
Storage | -20°C/1 year |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration | 1 mg/ml |
Observed Band | 250 |
Gene ID | MYO9B |
Alternative Name | MYO9B; MYR5; Unconventional myosin-IXb; Unconventional myosin-9b |
Background | myosin IXB(MYO9B) Homo sapiens This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-9 (MYH9). The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011], |
Type | polyclonal |