| Product Name | Nibrin (phospho Ser278) Polyclonal Antibody |
| Cat Number | HR1AP7446 |
| Source | Rabbit |
| Applications | WB,IF,ELISA |
| Species Reactivity | Human |
| Storage | -20°C/1 year |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Observed Band | 85 |
| Gene ID | NBN |
| Alternative Name | NBN; NBS; NBS1; P95; Nibrin; Cell cycle regulatory protein p95; Nijmegen breakage syndrome protein 1 |
| Background | nibrin(NBN) Homo sapiens Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008], |
| Type | polyclonal |