Product Name | Smad3 (4C9) Mouse mAb |
Cat Number | HR1AM2426 |
Source | Mouse |
Applications | WB, IHC |
Species Reactivity | Human,Rat,Mouse |
Recommended Dilutions | WB 1:1,000-2,000 IHC 1:100-200 |
Specificity | Human |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
Clonality | Monoclonal |
Isotope | IgG1 |
Concentration | 1mg/ml |
Observed Band | 52kDa |
Gene ID | 4088 |
Alternative Name | hMAD3 antibody, HSPC193 antibody, LDS1C antibody, MADH3 antibody, JV15 2 antibody |
Background | Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription. |
Type | monoclonal |