| Product Name | a-actinin (4A12) Mouse mAb |
| Cat Number | HR1AM2372 |
| Source | Mouse |
| Applications | IHC |
| Species Reactivity | Human,Rat,Mouse |
| Recommended Dilutions | IHC 1:100-200 |
| Specificity | Human |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Monoclonal |
| Isotope | IgG1 |
| Concentration | 1mg/ml |
| Observed Band | 103kDa |
| Gene ID | 87 |
| Alternative Name | actinin 1 smooth muscle antibody, actinin alpha 1 antibody, ACTN 1 antibody, FLJ40884 antibody |
| Background | ?-Actinin belongs to the spectrin family of cytoskeletal proteins. ?-Actinin is necessary for the attachment of actin filaments to the Z-lines in skeletal muscle cells, and to the dense bodies in smooth muscle cells. The functional protein is an anti-parallel dimer, which cross-links the thin filaments in adjacent sarcomeres, and therefore coordinated contractions between sarcomeres in the horizontal axis. |
| Type | monoclonal |