| Product Name | P63-? (3F11) Mouse mAb |
| Cat Number | HR1AM2515 |
| Source | Mouse |
| Applications | WB, IHC |
| Species Reactivity | Human,Rat,Mouse |
| Recommended Dilutions | WB 1:1,000-2,000 IHC:1;100-1:200 |
| Specificity | Human |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Monoclonal |
| Isotope | IgG1 |
| Concentration | 1mg/ml |
| Observed Band | 50-80kDa |
| Gene ID | 8626 |
| Alternative Name | N/A |
| Background | p63 can induce p53-responsive genes and apoptosis, mutation of p63 rarely results in tumors . Research investigators frequently observe amplification of the p63 gene in squamous cell carcinomas of the lung, head and neck . The p63 gene contains an alternative transcription initiation site that yields a 40 kDa ?Np63 lacking the transactivation domain, and alternative splicing at the carboxy-terminus yields the ?, ?, and ? isoforms . |
| Type | monoclonal |