Recombinant Human 4-1BB Receptor (TNFRSF9)

Recombinant Human 4-1BB Receptor (TNFRSF9)

Cat No.:HR2R1111
Product available

  Product info

Quantity: 20 μg

Gene Symbol: TNFRSF9
Product Details

Gene ID 3604
Accession Q07011
Alternative NameTumor necrosis factor receptor superfamily member 9, 41BB, 4-1BB ligand receptor, CDw137, T-cell antigen 4-1BB homolog, T-cell antigen ILA, CD137<br/>Recombinant Human 4-1BB (TNFRSF9)
SourceE. coli
Description 4-1BB Receptor (CD137) is a member of the TNF receptor superfamily expressed on activated CD4 and CD8 T cells as well as on activated natural killer cells. The binding of 4-1BB Receptor to its TNF family ligand, 4-1BB ligand (4-1BBL) delivers a co-stimulatory signal to resting T cells leading to high level IL2 production independently of CD28 signaling. Recombinant Human 4-1BB Receptor represents the soluble, cysteine-rich TNFR-like extracellular domain of 4-1BB Receptor.
Accession Q07011
Functions The ED50 as determined by dose dependent proliferation of human megakaryocytic leukemia cell line is &lt;0.5ng/ml.
FormulationLyophilized from 0.2 ?m filtered solution in PBS (pH 7.5)
Solubility A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Appearance Lyophilized Powder
Molecular Weight18
Purity>95% as determined by SDS-PAGE
Concentration <1.0 EU/μg of recombinant protein as determined by the LAL method
Shipping ConditionAmbient Temperature
Storage Condition Recombinant 4-1BB Receptor can be stored in working aliquots at 2? - 8?C for one month, or at -20?C to -70?C for twelve months. Avoid repeated freeze/thaw cycles.

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