Recombinant Mouse IL2


Recombinant Mouse IL2

Cat No.:HR2R2163
Product available

  Product info

Quantity: 1.0 μg

Gene Symbol: IL2
Product Details

Gene ID 16183
Accession P04351
Alternative NameIL-2, T-cell growth factor, TCGF<br/>Recombinant Mouse Interleukin-2 (IL2)
SpeciesMouse
SourceE. coli
Description IL-2 is produced mainly by T cells expressing the surface antigen CD4 following cell activation by mitogens or allogen. Interleukin-2 (IL-2) has multiple, sometimes opposing, functions during an inflammatory response. It is a potent inducer of T cell proliferation and Th1 and Th2 effector T cell differentiation and provides T cells with a long-lasting competitive advantage resulting in the optimal survival and function of memory cells. In a regulatory role, IL-2 is important for the development, survival, and function of regulatory T cells, it enhances Fas-mediated activation-induced cell death, and it inhibits the development of inflammatory Th17 cells. Thus, in its dual and contrasting functions, IL-2 contributes to both the induction and the termination of inflammatory immune responses.
Accession P04351
Functions The ED50 as determined by the dose dependent stimulation of murine CTLL-2 cells is &lt; 0.1 ng/mL, corresponding to a specific activity of &gt; 1 x 107 units/mg.
FormulationRecombinant mouse IL-2 was lyophilized from 0.2 ?m filtered PBS solution, pH 7.0.
Solubility A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Appearance Lyophilized Powder
Molecular Weight17
Purity>95% as determined by SDS-PAGE
Concentration <1.0 EU/μg of recombinant protein as determined by the LAL method.
Shipping ConditionAmbient Temperature
Storage Condition The lyophilized protein is stable for at least one year from date of receipt at -70?C. Upon reconstitution, this cytokine can be stored in working aliquots at 2? - 8?C for one month, or at -20?C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

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