Gene ID | |
Source | E.coli |
Description | Adenylate cyclase is an enzyme that converts adenosine triphosphate (ATP) into cyclic adenosine monophosphate (cAMP), a vital secondary messenger in numerous cellular signaling pathways. It plays a key role in mediating responses to extracellular signals by regulating cAMP levels, which in turn activate downstream effectors such as protein kinase A (PKA). Opiates have been shown to inhibit this enzyme and modify its activity. Additionally, calmodulin regulates adenylate cyclase by enhancing basal enzyme activity and amplifying activities involving GTP-binding proteins. |
Formulation | Lyophilized from 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0. |
Appearance | Lyophilized powder |
Molecular Weight | 56 kDa |
Purity | >85% (SDS-PAGE) |
Storage Condition | Store at -20?C/-80?C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |