Gene ID | N/A |
Accession | NM_001274 |
Alternative Name | CHEK1 |
Species | Human |
Source | Insect cells |
Description | CHK1 is a 56 kDa serine/threonine protein kinase that was originally identified in fission yeast to play a role in activation of the DNA damage checkpoint in the G2 phase of the cell cycle . CHK1 appears to function downstream of several of the known fission yeast checkpoint gene products, including that encoded by rad3+, a gene with sequence similarity to the ATM gene mutated in patients with ataxia telangiectasia . |
Accession | NM_001274 |
Functions | The specific activity of CHK1 was determined to be 144 nmol /min/mg as per activity assay protoco |
Formulation | 50mM NaPhosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol. |
Solubility | N/A |
Appearance | Liquid |
Molecular Weight | 59 |
Purity | 70% - 90% |
Shipping Condition | Dry Ice |
Storage Condition | Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |