Recombinant Human CK1 alpha 1 (N-GST tag)


Recombinant Human CK1 alpha 1 (N-GST tag)

Cat No.:HR2R1273
Product available

  Product info

Quantity: 10 μg

Gene Symbol: CK1a1
Product Details

Gene ID N/A
Accession NM_001892
Alternative NameCSNK1A1, CK1, HLCDGP1, PRO2975, CK1A1
SpeciesHuman
SourceInsect cells
Description CK1a1 is a member of the CK1 family of serine/threonine protein kinases which play an important role in diverse cell processes. CK1a1 can regulate Smo cell surface accumulation and activity in response to hedgehog. CK1a1 phosphorylate Smo at several sites and phosphorylation-deficient forms of Smo fail to accumulate on the cell surface and are unable to transduce the hedgehog signal . CK1a1 dynamically associates with the CBM complex on T cell receptor engagement to participate in cytokine production and lymphocyte proliferation. CK1a1 can form complex with MDM2 which then regulates the stability of p53 and E2F-1 transcription factors .
Accession NM_001892
Functions The specific activity of CK1a1 was determined to be 120 nmol /min/mg as per activity assay protocol.
Formulation50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Solubility N/A
Appearance Liquid
Molecular Weight62
Purity70% - 90%
Shipping ConditionDry Ice
Storage Condition Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

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