| Gene ID | 8995 |
| Accession | Q9UNG2 |
| Alternative Name | Activation-inducible TNF-related ligand, AITRL, Glucocorticoid-induced TNF-related ligand, GITRL, hGITRL, Tumor necrosis factor ligand superfamily member 18, TNFSF18, TL-6<br/>Recombinant Human Activation-Induced TNFR Member Ligand (TNFSF18) |
| Species | Human |
| Source | E. coli |
| Description | TNFSF18 is a transmembrane glycoprotein which is expressed in vascular endothelial cells as well as neurons, antigen presenting cells, CD4-CD8 double negative thymic precursors, and in the eye. TNFSF18 works to mediate the interactions between T cells and endothelial cells, and T cell growth. It has been shown that TNFSF18's expression is transiently up-regulated by proinflammatory stimulation. |
| Accession | Q9UNG2 |
| Functions | N.A. |
| Formulation | Lyophilized from a 0.2 micron filtered solution in Tris and salt |
| Solubility | Reconstitute at 0.1 mg/mL in PBS containing at least 0.1% human or bovine serum albumin. |
| Appearance | Lyophilized Powder |
| Molecular Weight | 14.2 |
| Purity | >95% as determined by SDS-PAGE |
| Concentration | < 1.0 EU/μg of recombinant protein as determined by the LAL method. |
| Shipping Condition | Ambient Temperature |
| Storage Condition | The lyophilized protein is stable for at least one year from date of receipt at -70?C. Upon reconstitution, this cytokine can be stored in working aliquots at 2? - 8?C for one month, or at -20?C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |