Gene ID | N/A |
Accession | NM_020666 |
Alternative Name | DKFZp686A20267 |
Species | Human |
Source | Insect cells |
Description | CLK4 or CDC-like kinase 4 belongs to the CDC2-like protein kinase (CLK) family that can interact with and phosphorylate the serine- and arginine-rich (SR) proteins. The SR proteins are known to play an important role in the formation of spliceosomes and thus may be involved in the regulation of alternative splicing. CLK4 expressed in E. coli phosphorylated myelin basic protein as a substrate as well as autophosphorylating itself but it did not phosphorylate H2B . |
Accession | NM_020666 |
Functions | The specific activity of CLK4was determined to be 12nmol/min/mg as per activity assay protocol. |
Formulation | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Solubility | N/A |
Appearance | Liquid |
Molecular Weight | 73 |
Purity | 70% - 90% |
Shipping Condition | Dry Ice |
Storage Condition | Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |