Recombinant Human CTACK (CCL27)


Recombinant Human CTACK (CCL27)

Cat No.:HR2R1295
Product available

  Product info

Quantity: 1.0 μg

Gene Symbol: CCL27
Product Details

Gene ID 10850
Accession Q9Y4X3
Alternative NameCTACK , C-C motif chemokine 27, CC chemokine ILC, Skinkine, ESkine, IL-11 R-alpha-locus chemokine, Small-inducible cytokine A27<br/>Recombinant Human Cutaneous T-cell-Attracting Chemokine (CCL27)
SpeciesHuman
SourceE. coli
Description CCL27 is a CC family chemokine which is expressed in epithelial cells and known to be up-regulated by inflammatory stimuli/wounded skin. CCL27 partakes in inflammation and wound healing ? by selectively attracting and directing CLA+ T cells into the skin, and inducing the migration of keratinocyte precursors from bone marrow to the skin. High levels of this chemokine in human serum though, have been linked to the severity of various diseases, one being atopic dermatitis.
Accession Q9Y4X3
Functions Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CCR10. The ED50 for this effect is typically 0.1-0.4 μg/mL.
FormulationLyophilized from a 0.2 ?m filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
Solubility Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin
Appearance Lyophilized Powder
Molecular Weight10.4
Purity>95% as determined by SDS-PAGE
Concentration <1.0 EU/μg of recombinant protein as determined by the LAL method.
Shipping ConditionAmbient Temperature
Storage Condition The lyophilized protein is stable for at least one year from date of receipt at -70?C. Upon reconstitution, this cytokine can be stored in working aliquots at 2? - 8?C for one month, or at -20?C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

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