Recombinant Human DRAK1 (STK17A) (N-GST tag)


Recombinant Human DRAK1 (STK17A) (N-GST tag)

Cat No.:HR2R1329
Product available

  Product info

Quantity: 10 μg

Gene Symbol: DRAK1 (STK17A)
Product Details

Gene ID N/A
Accession NM_004760
Alternative NameDRAK1; STK17A
SpeciesHuman
SourceInsect cells
Description DRAK1 (STK17A) is a member of the DAP kinase-related apoptosis-inducing protein kinase family. DRAK1 encodes an autophosphorylated nuclear protein with a protein kinase domain which has apoptosis-inducing activity. DRAK1 is capable of autophosphorylation and of phosphorylating myosin light chain as an exogenous substrate. The noncatalytic C terminus of DRAK1 is crucial for full kinase activity . DRAK1 is highly expressed in placenta, but also in heart, lung, skeletal muscle, kidney, and pancreas. DRAK1 act as a novel direct target of p53 and a modulator of cisplatin toxicity and reactive oxygen species in testicular cancer cells .
Accession NM_004760
Functions The specific activity of DRAK1 (STK17A) was determined to be 8.5 nmol /min/mg as per activity assay protocol
Formulation50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Solubility N/A
Appearance Liquid
Molecular Weight83
Purity70% - 90%
Shipping ConditionDry Ice
Storage Condition Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

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