Gene ID | N/A |
Accession | NM_004226 |
Alternative Name | DRAK2; STK17B |
Species | Human |
Source | Insect cells |
Description | ?DRAK2 is a member of the serine/threonine kinase family and is related to death-associated protein kinase that triggers apoptosis . DRAK2 is selectively important for T-cell survival and inhibition of DRAK2 has therapeutic potential for autoimmune disease . T-cell survival depends on a balance of T-cell receptor and co-stimulatory signals and deficiency of DRAK2 can affect autoimmune disease susceptibility without generalized suppression of the immune system (3). |
Accession | NM_004226 |
Functions | The specific activity of DRAK2 was determined to be 9.5 nmol /min/mg as per activity assay protocol. |
Formulation | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Solubility | N/A |
Appearance | Liquid |
Molecular Weight | 69 |
Purity | 70% - 90% |
Shipping Condition | Dry Ice |
Storage Condition | Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |