Recombinant Human DYRK3 (N-GST tag)


Recombinant Human DYRK3 (N-GST tag)

Cat No.:HR2R1333
Product available

  Product info

Quantity: 10 μg

Gene Symbol: DYRK3
Product Details

Gene ID N/A
Accession NM_001004023
Alternative NameRED, REDK, DYRK5
SpeciesHuman
SourceInsect cells
Description DYRK3 or dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 is belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. DYRK3 expressed in E. coli undergoes tyrosine autophosphorylation and catalyzes phosphorylation of histones H3 and H2B in vitro . DYRK3 regulate different steps of the caveolar cycle . DYRK3 can promote cell survival through phosphorylation and activation of SIRT1. DYRK3 directly phosphorylate SIRT1 at Thr(522), promoting deacetylation of p53.
Accession NM_001004023
Functions The specific activity of DYRK3 was determined to be242 nmol /min/mg as per activity assay protocol
Formulation50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Solubility N/A
Appearance Liquid
Molecular Weight95
Purity70% - 90%
Shipping ConditionDry Ice
Storage Condition Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

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