Recombinant Human EPHA2 (N-GST tag)


Recombinant Human EPHA2 (N-GST tag)

Cat No.:HR2R1356
Product available

  Product info

Quantity: 10 μg

Gene Symbol: EPHA2
Product Details

Gene ID N/A
Accession NM_004431
Alternative NameECK
SpeciesHuman
SourceInsect cells
Description EPHA2 is a member of the ephrin receptor subfamily of protein-tyrosine kinases that bind the ephrin-A ligand and have diverse cellular function. EPHA2 has been shown to be an oncoprotein of importance in a range of cancers. EPHA2 is overexpressed in several human cancer types and promotes malignancy through a mechanism involving RhoA-dependent destabilization of adherens junctions . EPHA2 overexpression induces a FAK-dependent increase in MMP-2 expression and invasiveness and this process that can be reversed by ligation of EPHA2 .
Accession NM_004431
Functions The specific activity of EPHA2 was determined to be 87 nmol/min/mg as per activity assay protocol
Formulation50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Solubility N/A
Appearance Liquid
Molecular Weight72
Purity70% - 90%
Shipping ConditionDry Ice
Storage Condition Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

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