Recombinant Human EPHB4 (N-His tag)


Recombinant Human EPHB4 (N-His tag)

Cat No.:HR2R1365
Product available

  Product info

Quantity: 10 μg

Gene Symbol: EPHB4
Product Details

Gene ID N/A
Accession NM_004444
Alternative NameHTK, MYK1, TYRO11, Mdk2
SpeciesHuman
SourceInsect cells
Description EPHB4 is a member of the Eph family of receptor tyrosine kinases which play a role in regulating cell adhesion and cell movement during embryonic development . Furthermore, because tissue disorganization and abnormal cell adhesion, movement, and survival characterize the more advanced stages of cancer, the inappropriate functioning of Eph receptor could play a causal role in malignancy . EPHB4 is uniquely expressed in the vascular endothelial and endocardial cells and animal knockout studies with EPHB4 reveal a phenotype that is similar to Ephrin B2 gene knockdown. Furthermore, EPHB4 has been shown to be the major essential interaction partner of Ephrin B2 in angiogenesis.?
Accession NM_004444
Functions The specific activity of EPHB4 was determined to be 410 nmol /min/mg as per activity assay protocol.
Formulation50mM sodium, pHosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.
Solubility N/A
Appearance Liquid
Molecular Weight50
Purity70% - 90%
Shipping ConditionDry Ice
Storage Condition Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

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