Recombinant Human FAK (N-GST tag)


Recombinant Human FAK (N-GST tag)

Cat No.:HR2R1377
Product available

  Product info

Quantity: 10 μg

Gene Symbol: FAK
Product Details

Gene ID N/A
Accession BC035404
Alternative NamePTK2; FADK; FAK1; FRNK; pp125FAK
SpeciesHuman
SourceInsect cells
Description ?FAK (Focal Adhesion Kinase) is a non-receptor protein tyrosine kinase involved in signal transduction from integrin-enriched focal adhesion sites that mediate cell contact with the extracellular matrix. FAK-enhanced signals have been shown to mediate the survival of anchorage-dependent cells and are critical for efficient cell migration in response to growth factor receptor and integrin stimulation . Elevated expression of FAK in human tumors has been correlated with increased malignancy and invasiveness . Elevated FAK expression in anaplastic astrocytoma and glioblastoma tumor biopsy samples has been demonstrated.
Accession BC035404
Functions The specific activity of FAK was determined to be 28 nmol /min/mg as per activity assay protocol.
Formulation50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Solubility N/A
Appearance Liquid
Molecular Weight140
Purity70% - 90%
Shipping ConditionDry Ice
Storage Condition Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

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