Recombinant Human ALK4 (N-GST tag)

Recombinant Human ALK4 (N-GST tag)

Cat No.:HR2R1138
Product available

  Product info

Quantity: 10 μg

Gene Symbol: ALK4
Product Details

Gene ID N/A
Accession NM_004302
Alternative NameACVR1B, SKR2, ACTRIB, ACVRLK4
SourceInsect cells
Description ALK4 is a member of the subfamily of receptor ser/thr kinases that mediates signaling by the Activins. ALK4 is expressed in many human tissues, including kidney, pancreas, brain, lung, and liver. Truncated ALK4, predominantly expressed in human pituitary adenomas, function as dominant negative receptors to interfere with wild-type receptor function and blocks the antiproliferative effect of activin possibly contributing to development of human pituitary tumors . ALK4 is able to mediate Nodal signaling in the presence of Cripto during vertebrate development .
Accession NM_004302
Functions The specific activity of ALK4 was determined to be 16 nmol /min/mg as per activity assay protocol.
Formulation50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Solubility N/A
Appearance Liquid
Molecular Weight64
Purity70% - 90%
Shipping ConditionDry Ice
Storage Condition Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

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