| Gene ID | N/A |
| Accession | NM_006251, NM_006253, NM_002733 |
| Alternative Name | Subunit A1: PRKAA1, MGC33776, MGC57364 Subunit B1: PRKAB1, AMPK, HAMPKb, MGC17785 Subunit G1: PRKAG1, AMPKG, MGC8666 |
| Species | Human |
| Source | Insect cells |
| Description | AMPK is a heterotrimer protein kinase consisting of an a catalytic subunit, and non-catalytic ? and ? subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status . In response to cellular metabolic stresses, AMPK is activated and phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating biosynthesis of fatty acid and cholesterol . |
| Accession | NM_006251, NM_006253, NM_002733 |
| Functions | The specific activity of AMPK was determined to be 737 nmol /min/mg as per activity assay protocol. |
| Formulation | 50mM NaPhosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol. |
| Solubility | N/A |
| Appearance | Liquid |
| Molecular Weight | 68 |
| Purity | 70% - 90% |
| Shipping Condition | Dry Ice |
| Storage Condition | Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |