| Gene ID |
2251 |
| Accession | P10767 |
| Alternative Name | FGF-6, Heparin secretory-transforming protein 2, HST-2, HSTF-2, Heparin-binding growth factor 6, HBGF-6<br/>Recombinant Human Fibroblast Growth Factor 6 (FGF6) |
| Species | Human |
| Source | E. coli |
| Description | FGF-6 is a heparin binding protein of the FGF family which works to control cell division, differentiation, and function. These proteins are especially prominent during prenatal development and postnatal growth. It has been shown that FGF-6 functions as a mitogen for fibroblasts, vascular endothelial cells, and prostate carcinoma cells (N-linked glycosylation is required for the full mitogenic effect). It has also been shown that FGF-6 inhibits the terminal differentiation of myoblasts, cooperates with TGF-2-beta to promote chondrogenesis in embryonic somites, and is present in leukemia cell lines which may undergo platelet megakaryocytic differentiation. |
| Accession | P10767 |
| Functions | Measured in a cell proliferation assay using NR6R-3T3 mouse fibroblast cells |
| Formulation | Lyophilized from a 0.2 ?m filtered solution in PBS |
| Solubility | Reconstitute at 10 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin. |
| Appearance | Lyophilized Powder |
| Molecular Weight | 19 |
| Purity | >95% as determined by SDS-PAGE |
| Concentration | < 1.0 EU/μg of recombinant protein as determined by the LAL method. |
| Shipping Condition | Ambient Temperature |
| Storage Condition | The lyophilized protein is stable for at least one year from date of receipt at -70?C. Upon reconstitution, this cytokine can be stored in working aliquots at 2? - 8?C for one month, or at -20?C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
