| Gene ID | 3958 |
| Accession | P17931 |
| Alternative Name | IgE-Binding Protein, Gal-3, 35 kDa lectin, Carbohydrate-binding protein 35, CBP 35, Galactose-specific lectin 3, Galactoside-binding protein, GALBP, L-31, Laminin-binding protein, Lectin L-29, Mac-2 antigen |
| Species | Human |
| Source | E. coli |
| Description | Gal-3 interacts, via its lectin domain, with glycoproteins and glycolipids on the surface of animal cells. It has been shown that nuclear Gal?3 can modulate gene expression while cytosolic Gal?3 can inhibit apoptosis and participate in exocytosis. Gal-3 is generally expressed by the epithelial cells of many tissues as well as by inflammatory cells. An increased level of Gal-3 expression may lead to some lymphomas, as well as thyroid and hepatic carcinomas while the down-regulation has been associated with breast and colon cancer. |
| Accession | P17931 |
| Functions | Measured by its ability to agglutinate human red blood cells. The ED(50) for this effect is typically 3-10 μg/mL. |
| Formulation | Lyophilized from a 0.2 ?m filtered solution in PBS. |
| Solubility | Reconstitute at 50 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin |
| Appearance | Lyophilized Powder |
| Molecular Weight | 26.1 |
| Purity | >95% as determined by SDS-PAGE |
| Concentration | < 1.0 EU/μg of recombinant protein as determined by the LAL method. |
| Shipping Condition | Ambient Temperature |
| Storage Condition | The lyophilized protein is stable for at least one year from date of receipt at -70?C. Upon reconstitution, this cytokine can be stored in working aliquots at 2? - 8?C for one month, or at -20?C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |