| Gene ID |
9573 |
| Accession | Q9NR23 |
| Alternative Name | GDF-3<br/>Recombinant Human Growth Differentiation Factor 3 (GDF3) |
| Species | Human |
| Source | E. coli |
| Description | GDF-3 is a growth and differentiation factor which belongs to the TGF-beta superfamily. GDF-3 and GDF-9 are the only two members of the family which do not form disulfide-linked dimers. GDF-3 has been found in adult bone marrow, spleen, thymus, and adipose tissue. Although signaling in all other members of the family involve the BMP receptors ALK1,2,3, and 6, GDF-3 signals through BMP receptors ALK4 and 7. |
| Accession | Q9NR23 |
| Functions | Measured by its ability to induce Smad2 phosphorylation in P19 mouse embryonal carcinoma cells. |
| Formulation | Lyophilized from a 0.2 ?m filtered solution in 10mM HCl & 5 μg BSA/μg of protein. |
| Solubility | Reconstitute at 0.1mg/mL in 4 mM HCl containing at least 0.1% human or bovine serum albumin. |
| Appearance | Lyophilized Powder |
| Molecular Weight | 13 |
| Purity | >95% as determined by SDS-PAGE |
| Concentration | <1.0 EU/μg of recombinant protein as determined by the LAL method. |
| Shipping Condition | Ambient Temperature |
| Storage Condition | The lyophilized protein is stable for at least one year from date of receipt at -70?C. Upon reconstitution, this cytokine can be stored in working aliquots at 2? - 8?C for one month, or at -20?C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
