Recombinant Human HER2 (N-GST tag)


Recombinant Human HER2 (N-GST tag)

Cat No.:HR2R1491
Product available

  Product info

Quantity: 10 μg

Gene Symbol: HER2
Product Details

Gene ID N/A
Accession NM_004448
Alternative NameNEU; NGL; HER2; TKR1; ERBB2; c-erb B2; HER-2/neu
SpeciesHuman
SourceInsect cells
Description HER2 gene encodes a cell-surface glycoprotein tyrosine kinase receptor with extensive homology to the epidermal growth factor receptor. HER2 is an oncogene and overexpression of unaltered HER2 coding sequences in NIH 3T3 cells results in cellular transformation and tumorigenesis . HER2 is amplified in about 30% of primary human breast malignancies and overexpression of HER2 is associated with the most aggressive tumors that show uncontrolled proliferation, resistance to apoptosis and increased motility .
Accession NM_004448
Functions The specific activity of HER2 was determined to be 11 nmol /min/mg as per activity assay protocol.
Formulation50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Solubility N/A
Appearance Liquid
Molecular Weight116
Purity70% - 90%
Shipping ConditionDry Ice
Storage Condition Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

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