Recombinant Human HIPK1 (N-GST tag)


Recombinant Human HIPK1 (N-GST tag)

Cat No.:HR2R1496
Product available

  Product info

Quantity: 10 μg

Gene Symbol: HIPK1
Product Details

Gene ID N/A
Accession NM_152696
Alternative NameMyak, Nbak2, KIAA0630, MGC26642, MGC33446, MGC33548
SpeciesHuman
SourceInsect cells
Description HIPK1 or homeodomain-interacting protein kinase 1 is a ser/thr protein kinase and a member of the HIPK family. HIPK 1 is a nuclear kinase that phosphorylates homeodomain transcription factors. HIPK1 phosphorylates DAXX and this leads to its relocalization and subsequent decrease in transcriptional repression activity . HIPK1also interacts with p53 and phosphorylates it on serine residues. HIPK 1 expression is elevated in breast cancer cell lines and embryonic fibroblasts from HIPK 1-null mice show more susceptibility to apoptosis induced by DNA damage .
Accession NM_152696
Functions The specific activity of HIPK1 was determined to be 79nmol /min/mg as per activity assay protocol.
Formulation50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Solubility N/A
Appearance Liquid
Molecular Weight71
Purity70% - 90%
Shipping ConditionDry Ice
Storage Condition Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

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