| Gene ID | 282617 |
| Accession | Q8IZI9 |
| Alternative Name | IL-28B, Interferon lambda-3, IFN-lambda-3, Cytokine Zcyto22, Interleukin-28C, IL-28C, ZCYTO22 <br/>Recombinant Human Interleukin-28B (IFNL3) |
| Species | Human |
| Source | CHO cells |
| Description | Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway. |
| Accession | Q8IZI9 |
| Functions | The activity was determined by a WISH cell viral resistance assay with a linear range of 4-20 ng/mL. |
| Formulation | Recombinant Human Interleukin-28B was lyophilized from a 0.2 ?m filtered PBS solution pH 7.4. |
| Solubility | A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
| Appearance | Lyophilized Powder |
| Molecular Weight | 23 |
| Purity | >95% as determined by SDS-PAGE |
| Concentration | <1.0 EU/μg of recombinant protein as determined by the LAL method. |
| Shipping Condition | Ambient Temperature |
| Storage Condition | The lyophilized protein is stable for at least one year from date of receipt at -70?C. Upon reconstitution, this cytokine can be stored in working aliquots at 2? - 8?C for one month, or at -20?C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |