| Gene ID |
27179 |
| Accession | Q9UHA7 |
| Alternative Name | IL-1 Epsilon, FIL1 epsilon, Interleukin-1 family member 6, IL-1F6, IL-36 gamma, IL-1F, IL-1H1<br/>Recombinant Human Interleukin-36 alpha (IL36A) |
| Species | Human |
| Source | E. coli |
| Description | IL-1 epsilon is an actively secreted member of the IL-1 family of cytokines. It is mainly expressed in tissues with epithelial cells and in psoriatic plaques, as well as by monocytes, B cells and T cells. IL-1 epsilon has been shown to signal through the IL-Rrp2 receptor which is primarily expressed on certain denditic cells, and to act as an agonist of NF-kappaB which then stimulates the inflammatory response in bronchial epithelial cells. |
| Accession | Q9UHA7 |
| Functions | N.A. |
| Formulation | Lyophilized from a 0.2 ?m filtered solution in PBS, NaCl and Tween? 20 with BSA as a carrier protein |
| Solubility | Reconstitute at 10 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin |
| Appearance | Lyophilized Powder |
| Molecular Weight | 17.4 |
| Purity | >95% as determined by SDS-PAGE |
| Concentration | < 1.0 EU/μg of recombinant protein as determined by the LAL method. |
| Shipping Condition | Ambient Temperature |
| Storage Condition | The lyophilized protein is stable for at least one year from date of receipt at -70?C. Upon reconstitution, this cytokine can be stored in working aliquots at 2? - 8?C for one month, or at -20?C for six months, with a carrier protein without detectable loss of activity.
Avoid repeated freeze/thaw cycles. |