| Gene ID |
3567 |
| Accession | P05113 |
| Alternative Name | IL-5, B cell growth factor II, BCGF-II, Cytotoxic T lymphocyte inducer, Eosinophil differentiation factor T cell replacing factor, TRF Recombinant Human Interleukin-5 (IL5) |
| Species | Human |
| Source | E. coli |
| Description | Interleukin 5 (IL5) is a specific hematopoietic growth factor that is responsible for the growth and differentiation of eosinophils. IL5 promotes the growth of immature hematopoietic progenitor cells BFU-E while it causes differentiation of CFU-E the proliferation of which is inhibited by IL5. B cells can be made responsive to IL5 by treatment with suboptimal doses of IL1. Interleukin 5 also promotes the generation of cytotoxic T cells from thymocytes. In thymocytes IL5 induces the expression of high affinity IL2 receptors. Human and mouse IL5 is cross-species reactive. Recombinant Human IL5 is a 26.5 kDa disulfide-linked homodimerized protein. |
| Accession | P05113 |
| Functions | N/A |
| Formulation | Lyophilized from a 0.2 ?m filtered solution in Tris with NaCl |
| Solubility | A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
| Appearance | Lyophilized Powder |
| Molecular Weight | 13 |
| Purity | >95% as determined by SDS-PAGE |
| Concentration | <1.0 EU/μg of recombinant protein as determined by the LAL method. |
| Shipping Condition | Ambient Temperature |
| Storage Condition | Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favourable performance, avoid repeated handling and multiple freeze/thaw cycles. |
