Recombinant Human IRAK2 (N-GST tag)


Recombinant Human IRAK2 (N-GST tag)

Cat No.:HR2R1642
Product available

  Product info

Quantity: 10 μg

Gene Symbol: IRAK2
Product Details

Gene ID N/A
Accession NM_001570
Alternative NameIRAK-2, MGC150550
SpeciesHuman
SourceInsect cells
Description ?Interleukin-1 receptor-associated kinase 2 (IRAK2) is important downstream signaling components of Toll-like receptors (TLRs) . IRAKs were first described as signal transducers for IL-1 and later have been implicated in signal transduction of other members of the Toll/IL-1 receptor family. The interleukin-1 receptor (IL-1R) signaling pathway leads to NF?B activation in mammals. To date, four mammalian IRAKs have been identified (IRAK-1, IRAK-2, IRAK-4, and IRAK-M) . It is believed that IRAK-2 could be an additional therapeutic target for inhibiting IL-1-induced inflammation.
Accession NM_001570
Functions The specific activity of IRAK2 was determined to be6 nmol /min/mg as per activity assay protocol.
Formulation50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Solubility N/A
Appearance Liquid
Molecular Weight103
Purity70% - 90%
Shipping ConditionDry Ice
Storage Condition Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

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