Gene ID | N/A |
Accession | Q6VAB6 |
Alternative Name | none |
Species | Human |
Source | Insect cells |
Description | KSR2 or kinase suppressor of Ras 2 specifically regulates the activity of MEKK3 and COT but not other members of the MAP3K family . KSR interacts with a regulatory Raf molecule in cis to induce a conformational switch of MEK, facilitating MEK's phosphorylation by a separate catalytic Raf molecule in trans . |
Accession | Q6VAB6 |
Functions | The specific activity of KSR2 was determined to be 150 nmol /min/mg as per activity assay protocol. |
Formulation | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Solubility | N/A |
Appearance | Liquid |
Molecular Weight | 72 |
Purity | 70% - 90% |
Shipping Condition | Dry Ice |
Storage Condition | Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |