| Gene ID | N/A |
| Accession | NM_002344 |
| Alternative Name | TYK1 |
| Species | Human |
| Source | Insect cells |
| Description | LTK is a member of the ros/insulin receptor family of tyrosine kinases. LTK express a gene encoding a putative transmembrane protein-kinase devoid of an extracellular domain and it may encode a signal transduction subunit for one or more of the hematopoietic receptors . LTK gene produces not only the putative receptor tyrosine kinase for an unknown ligand but also multiple protein products that may have different functions . LTK causes upregulation of the PI3K pathway and possibly form a genetic component of susceptibility to abnormal proliferation of self-reactive B cells in SLE (3). |
| Accession | NM_002344 |
| Functions | The specific activity of LTK was determined to be 15 nmol /min/mg as per activity assay protocol. |
| Formulation | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
| Solubility | N/A |
| Appearance | Liquid |
| Molecular Weight | 70 |
| Purity | 70% - 90% |
| Shipping Condition | Dry Ice |
| Storage Condition | Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |