| Gene ID | 6375 |
| Accession | P47992 |
| Alternative Name | ATAC, C motif chemokine 1, Cytokine SCM-1, Lymphotaxin, SCM-1-alpha, Small-inducible cytokine C1, XC chemokine ligand 1, XCL1, LTN, SCYC1 |
| Species | Human |
| Source | E. coli |
| Description | XCL1, also known as lymphotactin or ATAC, is the sole member of the C subgroup of chemokines, and more importantly, is produced mainly by activated CD8 T cells (and to a lesser extent by natural killer and mast cells). The chemotactic activity of XCL1 is restricted to lymphocytes and has no effect on monocytes. |
| Accession | P47992 |
| Functions | Activity was determined by the ability to induce chemotaxis of human T-cells at concentrations ranging between 50-100 ng/ml. |
| Formulation | Recombinant Lymphotactin was lyophilzed from 0.2?m filtered PBS, pH 7.0. |
| Solubility | A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
| Appearance | Lyophilized Powder |
| Molecular Weight | 10 |
| Purity | >95% as determined by SDS-PAGE |
| Concentration | <1.0 EU/μg of recombinant protein as determined by the LAL method. |
| Shipping Condition | Ambient Temperature |
| Storage Condition | The lyophilized protein is stable for at least one year from date of receipt at -70?C. Upon reconstitution, this cytokine can be stored in working aliquots at 2? - 8?C for one month, or at -20?C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |