| Gene ID |
7873 |
| Accession | P55145 |
| Alternative Name | Arginine-rich protein, Protein ARMET, ARP<br/>Recombinant Human Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) |
| Species | Human |
| Source | E. coli |
| Description | MANF is a neurotrophic factor found mainly in central nervous tissues where it may remain localized to the endoplasmic reticulum and in the Golgi apparatus, or secreted. It has been shown that MANF plays an important role in protecting cells against tunicamycin and thapsigargin-induced cell death. Without MANF, cells become increasingly vulnerable to the aforementioned drugs. Also, MANF is structurally homologous to CDNF. |
| Accession | P55145 |
| Functions | N.A. |
| Formulation | Lyophilized from a 0.2 ?m filtered solution in PBS |
| Solubility | Reconstitute at 200 μg/mL in PBS |
| Appearance | Lyophilized Powder |
| Molecular Weight | 18.4 |
| Purity | >95% as determined by SDS-PAGE |
| Concentration | < 1.0 EU/μg of recombinant protein as determined by the LAL method. |
| Shipping Condition | Ambient Temperature |
| Storage Condition | The lyophilized protein is stable for at least one year from date of receipt at -70?C. Upon reconstitution, this cytokine can be stored in working aliquots at 2? - 8?C for one month, or at -20?C for six months, with a carrier protein without detectable loss of activity.
Avoid repeated freeze/thaw cycles. |
