| Gene ID | N/A |
| Accession | NM_139355 |
| Alternative Name | CHK; CTK; HHYLTK; HYL; HYLTK; LSK |
| Species | Human |
| Source | Insect cells |
| Description | MATK belongs to tyrosine protein kinase family, CSK subfamily. It inactivates Src family kinase activity by specifically phosphorylating their C-terminal regulatory tyrosine residue and may plays a significant role in the signal transduction of hematopoietic cells . MATK binds to the phosphorylated Tyr568/570 sites on c-KIT to which FYN binds and leads to the down-regulation of FYN . MATK has been shown to be involved in signaling in some cases of breast cancer. |
| Accession | NM_139355 |
| Functions | The specific activity of MATK (CTK)was determined to be 11nmol /min/mg as per activity assay protocol. |
| Formulation | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
| Solubility | N/A |
| Appearance | Liquid |
| Molecular Weight | 83 |
| Purity | 70% - 90% |
| Shipping Condition | Dry Ice |
| Storage Condition | Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |